Contributed by Cory Schlesener Bacterial genomes are composed of diverse genetic elements. Many of these elements are not exclusively passed down a parental lineage (vertically acquired), but can also be horizontally acquired from other bacteria of varying degrees of relatedness. As bacteria are asexual, mechanisms of horizontal transfer of genetic information provide ways to add diversity to a population. Novel genes […]
Contributed by Cory Schlesener It is useful to apply known biological concepts to empower bioinformatics to make the most out of analyzing genetic sequences (in proper context). Here is an example of a simple genetic analysis that can carry a lot of meaning when applied in a specific context. Zinc finger antiviral protein (ZAP) is […]
Contributed by Ashleigh Flores There has been growing interest in the link between the microbiota of the gut and disease mediated changes in both human and veterinary medicine. The horse gastrointestinal tract is one of the most unique displays of physiological engineering in any mammal. Horses are non-ruminant herbivores with the ability for microbial fermentation […]
Biological Machine Learning Combined with Campylobacter Population Genomics Reveals Virulence Gene Allelic Variants Cause Disease
Pandemic dynamics of COVID-19 using epidemic stage, instantaneous reproductive number and pathogen genome identity (GENI) score: modeling molecular epidemiology Biological machine learning combined with bacterial population genomics reveals common and rare allelic variants of genes to cause disease Salmonella Enhances Osteogenic Differentiation in Adipose-Derived Mesenchymal Stem Cells
Contributed by DJ Bandoy, DVM Covid-19 is the name given by the World Health Organization to the severe respiratory disease due to 2019-nCOV. What is astonishing is the speed of release of preprints in Biorkiv of several studies from phylogenetics to virus pseudotyping. While public health concern triumphs over the need for peer review, uncurated […]
Contributed by DJ Darwin Bandoy, DVM I personally believe that biology is a big data puzzle. That is also the main reason why I took my PhD in the Weimer lab with the 100K Pathogen Genome Project. But when I started in the lab, I also realized that before you can do any biology with […]
Click on the link to read the latest manuscript that Dr. Weimer was involved with which has been published in Nature. Food authentication from shotgun sequencing reads with an application on high protein powders.
Contributed by Darwin Bandoy, DVM Antimicrobial resistance is a key issue as pathogens develop resistance due to the misuse of antimicrobials in food animals. While some countries have already banned the use of antibiotics as growth promotants, emerging economies find it difficult to implement due to numerous factors. From a monitoring point of view, large […]
Contributed by DJ Darwin Bandoy, DVM Catching up with scientific literature is definitely a big challenge. While Google makes it easy to find materials you are searching for, it is not easy for articles that are tangential to your interest. These are the type of readings outside your field of interest but can complement your […]