Nature – Pathogens
- Systemic inflammation impairs myelopoiesis and interferon type I responses in humans April 18, 2025
- The utility of neonatal sequential organ failure assessment in mortality risk in all neonates with suspected late-onset infection April 18, 2025
- Transcriptomic profiling of severe and critical COVID-19 patients reveals alterations in expression, splicing and polyadenylation April 18, 2025
- Prevalence of hepatitis C virus infection in Qatar’s resident population based on a national screening campaign April 18, 2025
- Bivalent mRNA booster vaccination recalls cellular and antibody immunity against antigenically divergent SARS-CoV-2 spike antigens April 18, 2025
Nature – AMR
- Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis April 18, 2025
- Hotspot gene conversion between FKS1 and FKS2 in echinocandin resistant Candida glabrata serial isolates April 17, 2025
- Clinical and genetic analysis of oral and nasal staphylococcus aureus isolates in dental patients April 16, 2025
- Genomic epidemiology and characterization of difficult-to-treat resistant Pseudomonas aeruginosa isolates co-harboring blaOXA-50 and crpP causing bronchiectasis April 15, 2025
- Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China April 14, 2025
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Category Archives: uncategorized
Creating Prokaryotic Taxonomies with Whole Genomes
Contributed by Cory Schlesener, B.S. Historically it has been difficult to categorize prokaryotes into taxonomic units. Advances made have utilized DNA sequence identity to profile organisms at a higher resolution. Older technologies based on genomic DNA hybridization, or sequence comparison … Continue reading
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Year Four
Contributed by DJ Darwin Bandoy, PhD Candidate I am now in my year four of my PhD studies in Integrative Pathobiology in UC Davis, still in the middle of the COVID-19 Pandemic. I presented in the lab meeting yesterday the … Continue reading
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New Quality Control Program Optimized for Long Read Nucleotide Sequencing
Contributed by Cory Schlesener, B.S. DNA sequencing, in a high throughput process, generates errors in the reads, such as low confidence nucleotide based calling. Quality control is needed to evaluate the quality of the sequencing output and identify undesired features. … Continue reading
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Gut Microbiota and Unhealthy Aging
Contributed by Carol Huang, Sr. Research Specialist @BartWeimersLab The equilibrium of gut microbiota is fundamental to our health. The gut microbiota composition established at birth which changes with aging, diet, … Continue reading
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Where is the metadata?
Contributed by DJ Darwin Bandoy, PhD Candidate One distinguishing feature of this pandemic is the rapid release of whole genome sequencing data. These sequences are usually uploaded in public databases with minimal accompanying metadata. While dates and geographic origin are … Continue reading
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Quantify Structural Similarity Comparisons of Genome Assemblies
Contributed by Cory Schlesener, B.S. One important component of a genome’s overall composition is the larger structure of how conserved blocks of genetic sequence are arranged. As segments of DNA recombine, sequences are introduced into new locations and/or orientations in a … Continue reading
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More on the Equine Microbiome
Contributed by Ashleigh Flores, M.S. Within the GI Tract, horses can host up to 1015 bacterial cells, with the highest population residing within the caecum. Recent studies have revealed that distinct individual ecosystems for each compartment of the equine gut … Continue reading
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Pandemic Status as of July 12, 2020
Contributed by DJ Darwin Bandoy, Ph.D. Candidate California is in full lockdown again after a surge in cases. This is a consequence of opening too early when the cases are not fully suppressed. This requires people to wear masks, practice … Continue reading
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Professor Bart C. Weimer, Ph.D.
Professor, School of Veterinary Medicine, UC Davis Director, 100K Pathogen Genome Project Publication Summary: 22 book chapters 4 books 159 manuscripts 6 patents awarded 13 invention disclosures 540 presentations Google Scholar, ResearchGate, Orcid, ReseacherID (Publons) UCDavis Microbiome Special Research Program Leadership … Continue reading
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Horses and “Pigeon Fever”
Contributed by Ashleigh Flores, M.S. Corynebacterium pseudotuberculosis biovar equi is responsible for the highly contagious disease in horses commonly known as “Pigeon Fever”. Although flies act as the primary vector, soil serves as a reservoir for this robust microorganism. Research … Continue reading
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