Category Archives: uncategorized

Herpesvirus Latency Confers Protection From L. monocytogenes and Y. pestis

Contributed by Azarene Foutouhi Susceptibility to bacterial infections depends on many things including the individual’s immunologic condition and the virulence of the bacteria. After preliminary data showed prolonged macrophage activation during gamma-Herpesvirus latency, researchers wondered if this state might be associated with resistance to infection. Mice five weeks post infection with HV68 or MCMV challenged […]

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Genetic memory: accessing the past through our DNA

Contributed by Poyin Chen The premise for the video game, Assassin’s Creed, is based on the technological ability to re-live our ancestors’ experiences by accessing their memories inherited through their DNA. While this is actually scientifically impossible, the concept of heritable “memories” through epigenetic programming is currently an active area of study. A publication by […]

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Amylases and their importance during glycan degradation

Contributed by Narine Arabyan Amylases catalyze the cleavage of α-D-1,4 and α-D-1,6-glycosidic bonds in starch and related carbohydrates. Amylases are widely distributed in nature and are important in carbohydrate metabolism. Amylases in Salmonella are poorly characterized glycosyl hydrolases. The importance of amylases during Salmonella infection is understudied, especially as new virulence factors. The genome of […]

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Communicating Goals and Expectations

Contributed by B. Carol Huang Goal setting is very important for anyone who wishes to have an achievement. The goal is like a blueprint for a building project, a road map for a journey, in which it will answer the questions like what, why, how and when. What: answers destination, mission, and vision. Why: answers the importance […]

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3-D tissue culture models to mimic human gut infections

Contributed by Nguyet Kong 3-D tissue culture models to mimic human gut infections In an article from npj Microgravity, scientists have reported their latest advancement in 3-D intestinal model development where they want to develop more realistic model to prevent Salmonella from causing food poisoning and disease around the world. Salmonella infections have increase over the […]

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Science vs politics?

Contributed by Ning Chin The advancement in science is often pursued because technological improvement is supposed to improve our life. Researches in biological sciences are especially important to improve our health and general wellbeing. But science does not get implemented in our daily life quick enough. This is partly due to the rigorous self-policing nature […]

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Sequencing and publication of 306 Listeria monocytogenes genomes

Contributed by Poyin Chen Listeria monocytogenes is a foodborne pathogen prevalent in environmental and food matrices including soil, fruit, and deli meats. This organism encompasses 13 serotypes, among which serotypes 1/2a, 1/2b, and 4b are most commonly associated with disease including gastroenteritis and abortions. Listeriosis accounts for less than 1% of foodborne illnesses worldwide yet […]

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Importance of sialidases during infection

  Contributed by Narine Arabyan Sialidases, also known as neuraminidases, are widely distributed in nature and are found in organisms from Eukarya, Eubacteria, and viruses. Sialidases are glycosyl-hydrolases that cleave the α-ketosidic bond of a terminal sialic acid residue from complex glycans. Sialidases have been implicated and correlated with several diseases. Sialidases play a critical […]

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